Scientist / Senior Scientist, Directed Evolution

Company: Glyphic Biotechnologies
Location: Berkeley
Posted on: June 23, 2022

Job Description:

Scientist / Senior Scientist - Directed EvolutionBerkeley, CA or New York City, NYAt Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule protein sequencing platform that will transform proteomics and usher in a new era of insights into human biology and disease. To achieve this vision, we want your help.---Job SummarySeeking a highly motivated Scientist / Senior Scientist with experience in quantitative biology and protein engineering to develop, apply and scale novel technologies. The successful candidate will possess a PhD in bioengineering, computational biology, or related fields with an emphasis on protein structure and function. Previous experience with high-throughput experimentation and laboratory automation is preferred.Responsibilities

• Developing experimental and computational methods to discover and reprogram enzyme target specificity or protein binding affinity.
• Screening and maturing protein variants using experimental methods such as PACE, phage-display , yeast-display, or other evolution methodologies.
• Designing and developing automated high-throughput laboratory pipelines.
• Analyzing high-throughput data to drive experimentation.Requirements
  • PhD in bioengineering, computational biology, or related field.
  • Needs to be interest in working outside of one specialties
  • In depth molecular biology experience: cloning, protein purification, next generation sequencing, qPCR, etc.
  • Ideal experience with evolving enzymes for enhanced specificity and/or specificity reprogramming.
  • Experience building high-throughput automated experimental pipelines.
  • Experience in data-driven quantitative biology.
  • Of interest, but not necessary: ability to design quantitative protocols for use in machine learning or similar data-driven feedback mechanisms.
  • Experience with molecular visualization software such as PyMOL or similar is preferred.
  • Team player with excellent verbal and written communication skills.
  • Previous experience managing either RAs or undergraduates.Benefits
    • Health Care Plan (Medical, Dental & Vision)
    • Commuter (Public Transit, Parking)
    • Paid Time Off (Vacation, Sick & Public Holidays)
    • Family Leave (Maternity, Paternity)
    • Retirement (401(K))
    • Training & Development---Individuals seeking employment at Glyphic Biotechnologies are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.

Keywords: Glyphic Biotechnologies, Berkeley , Scientist / Senior Scientist, Directed Evolution, Other , Berkeley, California