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Senior Process Development Research Associate

Company: Agenus
Location: Berkeley
Posted on: June 24, 2022

Job Description:

DESCRIPTION: Agenus is an immuno-oncology company designed to deliver innovation with speed for patients with cancer. We have a unique portfolio of antibodies, vaccines, cell therapies (through our AgenTus Therapeutics subsidiary) and adjuvants designed to treat cancers with optimal combinations. In addition to our broad portfolio, we have an accomplished team of scientists, novel technology platforms and end-to-end capabilities from new target discovery to GMP manufacturing. We believe that combination therapies and a deep understanding of each patient's cancer will be key drivers of success in substantially expanding the patient population benefiting from current immuno-oncology therapies. At Agenus, we believe we have assembled the capabilities to bring curative treatments to patients.
Who are we looking for?

  • An enthusiastic and knowledgeable Process Development Associate to join our Upstream Process Development team
  • A colleague that can leverage their industry and or academic knowledge and experience in cell culture to support development of upstream processes that advance our pipeline programs
  • A colleague who is adept at working on multiple projects in a fast-paced environment
  • An individual with a desire to learn, trouble shoot technical problems and work as part of a team
    What are we looking for?
    • Creativity: Innovative thinker and learning-agile team member
    • Ownership: A partner to jointly own our company's goals, execution and success
    • Working together: A colleague to thrive in collaboration with our global teammates
    • Loving what you do: A team member with positive energy that is passionate about our mission
    • Engagement: An active participant that enjoys sharing ideas, contributing with others, and engaging in our projects and process improvements.
      What are we offering?
      • A dynamic, fun and learning culture
      • Exposure to pioneering science and the full drug development process
      • A team with experience and passion about science
      • A unique opportunity to help develop the platforms and strategy of a burgeoning company
      • Career support and learning opportunities within Agenus
      • Membership within a growing, dynamic and collegial organization
      • Advanced technologies and potential for cross-training across different functional groups
        Job ResponsibilitiesThis position will primarily focus on conducting CHO cell culture evaluation and process development in shake flasks and bench scale bioreactors. The successful candidate will be involved in upstream process development of our pipeline programs, including clone evaluation, process parameter optimization, and generation of material to support downstream and analytical development. Strong aseptic techniques and laboratory skills and experience in mammalian cell culture procedures is required. Will require some occasional weekend/off-shift work as needed.
        Roles and Responsibilities - Generate materials in mini to small-scale bioreactors to support R&D, downstream and analytical development. - Participate in planning, design and execution of upstream process development/optimization experiments; interpret and present experimental results - Perform cell line evaluation in shake flasks and bioreactors and generate technical reports - Maintain accurate data recording in laboratory notebooks and draft scientific reports as required - Compile data for technical reports using Microsoft Office and present scientific results at internal team meetings - Maintain laboratory supplies and a safe and clean laboratory environment
        Qualifications and Educational Requirements - Master's degree or native equivalent in scientific discipline with 3-5 years relevant experience; or Bachelor's degree or native equivalent with 5+ years relevant experience.
        Supplementary Skills: - Excellent mammalian cell culture and aseptic techniques - Some knowledge of cGMP manufacturing processes including experience with Ambr bioreactor system - Previous experience with Finesse Controller (DeltaV) and Eppendorf DasGip bioreactor systems
        Competencies: - Strong organizational and time management skills
        Effective verbal and written communication. Ability to work effectively both independently and in a team setting

Keywords: Agenus, Berkeley , Senior Process Development Research Associate, Other , Berkeley, California

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