Senior Principal Scientist / Distinguished Scientist - Structural Biology
Company: Genentech
Location: Berkeley
Posted on: January 18, 2023
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Job Description:
The PositionThe Genentech Structural Biology Department
integrates macromolecular crystallography, CryoEM, and NMR
spectroscopy to both drive drug discovery as well as uncover
fundamental biology. We explore the structural and functional
properties of proteins of therapeutic interest, and their
interactions with ligands, substrates, and binding partners. Our
group designs constructs, purifies proteins, and then analyzes
their structures and molecular interactions. - -We collaborate with
scientists throughout the Research organization to advance both
traditional "small molecule" and protein-based drug discovery as
well as to pursue basic research questions regarding structure and
function.Who you are:Macromolecular structural biologist with
outstanding experience in all aspects of structure determination,
from construct design through refinement, interested in joining a
multi-disciplinary structural biology department, to pursue drug
design and to perform groundbreaking research. - -A key requirement
is a track record of working with chemistry teams in structure
based drug design.Requirements:Ph.D. in structural biology,
biophysics, biochemistry or related discipline, relevant post
doctoral experience, and 10-15 years additional experience as an
independent scientific investigator or group leader. Knowledge of
protein purification, fundamental biochemistry, and a strong
publication record in top tier journals as well as significant
technical expertise in determining X-ray crystalstructure and
CryoEM structures is required. Significant (10+ years of) prior
experience working with protein:ligand complexes for mechanistic
studies and/or drug discovery are required. Facility with standard
software related to structure determination and data presentation
is expected. As this position interfaces with multiple groups at
Genentech, high quality verbal, written, and presentationskills are
essential.** Please include a cover letter with your resume
submission **#scientistjob#LI-GD2Relocation benefits are available
for this job postingThe expected salary range for this position
based on the primary location of California is $168,00-$313,000. -
Actual pay will be determined based on experience, qualifications,
geographic location, and other job-related factors permitted by
law. - A discretionary annual bonus may be available based on
individual and Company performance. - This position also qualifies
for the benefits detailed at the link provided below.Genentech is
an equal opportunity employer, and we embrace the increasingly
diverse world around us. Genentech prohibits unlawful
discrimination based on race, color, religion, gender, sexual
orientation, gender identity or expression, national origin or
ancestry, age, disability, marital status and veteran
status.Genentech requires all new hires to be fully vaccinated
against COVID-19 as of their start date. This requirement is a
condition of employment at Genentech, and it applies regardless of
whether the position is located at a Genentech campus or is fully
remote. - If you are unable to receive the vaccine due to a
disability or serious medical condition, or because it is
prohibited as a result of your sincerely held religious beliefs,
you will have an opportunity to request a reasonable
accommodation.Job Facts JOB FUNCTION COMPANY/DIVISION Genentech
SCHEDULE JOB TYPE Full time
Keywords: Genentech, Berkeley , Senior Principal Scientist / Distinguished Scientist - Structural Biology, Other , Berkeley, California
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