Associate Biochemist - Gene Therapy
Company: EUROFINS SCIENT.
Location: Berkeley
Posted on: January 27, 2023
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Job Description:
Consider joining Eurofins Lancaster Laboratories where people
are the most important element in our chemistry. Eurofins is a
leading international group of laboratories providing an
unparalleled range of testing and support services to the
pharmaceutical, biopharmaceutical, food, environmental, and
consumer products industries and to governments. Eurofins Lancaster
Laboratories, a nationally recognized laboratory, is searching for
an Associate Biochemist - Gene Therapy fto support our Professional
Scientific Services group in Berkeley, CA. Associate Biochemist
responsibilities include, but are not limited to, the following: *
Performs and conducts bench scale gene therapy Adeno-Associated
virus (AAV) vector purification development experiments
independently (e.g. buffer preparation, chromatography, tangential
flow filtration, unit operation procedures, assays, etc.) with
general guidance and instruction
* Evaluates new methods, technologies, and equipment as required
for AAV viral vector and monoclonal antibody purification to
facilitate and improve process development
* Designs AAV purification experiments, data analysis, trouble
shooting, protocol and report writing under the direction of the
development lead scientist
* Executes pilot scale-up AAV viral vector purification runs and
supports clinical manufacturing operations under GMP conditions, as
needed
* Exercises judgment within defined practices and policies in
determining appropriate action, and is capable of understanding
technical literature for problem solving
* Communicates scientific findings, provides status updates on
assigned tasks in one-on-one discussions and within the project
team and department meetings
* Contributes to the functions of the laboratory including
ordering, organization, chemical and equipment monitoring, and
maintenance The ideal candidate would possess: * Ability to
understand and execute bench scale purification development
techniques including chromatography using AKTA and Avant
workstations, dead-end filtration, tangential flow filtration, and
various protein and viral vector analytical assays such as
SDS-PAGE, Western Blotting, UV-Vis Spectrophotometry, HPLC, qPCR,
ELISA, DLS, and HTRF
* Understands basic GMP requirements
* Familiar with statistical software such as JMP for data
analysis
* Experience with Design of Experiment (DOE), automation, database
construction and analysis
* Experience working with automated liquid handler (e.g. Tecan) and
automated UFDF systems (e.g. AKTA Crossflow and AKTA Flux)
* Bachelor degree in chemistry, biology, or other related degree
concentration
* 1-3 years of relevant experience (BS degree) or 0-1 year of
relevant experience (MS degree)
* Authorization to work in the United States indefinitely without
restriction or sponsorship Position is full-time, Monday through
Friday (8 a.m.-5 p.m.), with overtime as needed. Candidates
currently living within a commutable distance of Berkeley,
California are encouraged to apply. As a Eurofins Lancaster Lab PSS
employee, you will become part of a company that has received
national recognition as a great place to work. We offer excellent
full-time benefits including comprehensive medical coverage, life
and disability insurance, 401(k) with company match, paid holidays
and vacation, personal days, and dental and vision options. To
learn more about Eurofins Lancaster Laboratories, please explore
our website . Eurofins is a M/F, Disabled, and Veteran Equal
Employment Opportunity and Affirmative Action employer.
Keywords: EUROFINS SCIENT., Berkeley , Associate Biochemist - Gene Therapy, Other , Berkeley, California
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